Our RESETTM clinical trials with rese-cel (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, and pemphigus vulgaris are now recruiting.

Join Our Crew

Associate Laboratory Manager

Philadelphia, PA

About the Position

At Cabaletta we are applying our Cabaletta Approach to B cell Ablation (CABA) to develop T cell therapies to transform the lives of patients with autoimmune diseases. Reporting to the Head of Lab Operations, the Associate Laboratory Manager will support the operations, leadership, direction, and administration of our growing laboratory space, including a longer-term opportunity with new lab build out. The role will offer opportunities to work and cultivate skills within the cellular, molecular, and biochemical arenas, as well as inventory management and waste disposal/safety procedures.

Responsibilities Include

  • Daily upkeep of laboratory space, including but not limited to, restocking of supplies, biological waste disposal, and preparation of media, buffers, and solutions.
    • Lead daily startup (when applicable) requirements for specialty equipment.
    • Assist with equipment monitoring including alarm system and annual maintenance across multiple teams and lab spaces.
    • Compressed gas tank movement and change out. Must be capable of pushing 230-Liter LN2 tank on wheels.
  • Support inventory management and purchasing activities by maintaining organizational oversight of laboratory supplies and restocking processes.
    • Including inputting items into inventory management and weekly checks.
    • Maintain cold storage inventory within the core laboratory lab spaces
    • Help maintain variety of documentation across lab ops e.g. IOPQs, PMs, COA/COC, calibrations
  • Support quote and purchase order organization
  • Point person for equipment cleaning efforts throughout all lab spaces e.g. incubators, centrifuges, water/bead baths.
  • Assist in equipment cleaning maintenance records, including collection and technical review 
    • Aids in deviations associated with equipment maintenance records, working closely with quality representatives
  • Assist in providing lab access for external personnel e.g. vendors, field service engineers, and building management.
  • Assist with biannual pipette calibration including collection, document review and input into Cabaletta’s equipment management system.
  • Support implementation of laboratory guidelines and standard operating procedures consistent with GxP requirements.

Required Qualifications

  • Bachelor’s degree in a scientific discipline with 1+ years of experience.
  • Aseptic technique and general lab experience e.g. cell culture maintenance, preparing laboratory reagents for experimental use, molecular or biochemical assays, protein or bacteria work.
  • Must be able to lift ~40lb onto a cart and ~10lb over your head.
  • Foundational understanding of laboratory equipment.
  • Strong attention to detail and organizational skills are required.
  • Clear written and verbal communication skills and an ability to work independently.
  • Proactive attitude and helpful mindset.
  • Strong team orientation and passion for continuous self-development.

Preferred Qualifications:

  • Experience with sample/inventory tracking and management.
  • Experience with LIMS or ELN
  • Foundational knowledge of GDP, GLP
  • A high level of flexibility to support various other activities; the ability to learn new techniques outside of existing field of expertise.
  • Two plus years of lab operations experience within industrial or academic settings


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How to Apply

Please click the link at the bottom of the posting to submit an application.

Benefits

Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.