Our RESETTM clinical trials with rese-cel (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, and pemphigus vulgaris are now recruiting.

Join Our Crew

Research Associate/Sr. Research Associate

On-Site/Philadelphia, PA

About the Position

Reporting to Senior Scientist, Cellular Immunology, Preclinical Research, we are seeking an experienced, motivated, detail-oriented, and highly skilled Research Associate/Sr. Research Associate to join our preclinical research team. Under scientific and technical supervision, the individual will perform various cell-based assays and other in vitro and ex vivo based assays to contribute to the discovery and development of novel therapeutics at Cabaletta. Additionally, the individual will be responsible for cell line generation and maintenance to assist in the development of novel cell-based assays for the Cellular Immunology team. The position allows for potential impact in additional areas within Cabaletta, including molecular biology, immunology, and cell therapy development.

Responsibilities Include

  • Maintain and expand, bank, and manage various cell lines, including primary cells
  • Cell line generation using lentivirus technology for suspension cell lines.
  • Perform cytotoxicity and other cell-based assays
  • Perform IND-enabling assays following SOPs and proper documentation
  • Perform lab associated tasks in accordance with cGLP and Cabaletta Bio lab safety policies and SOPs.
  • Maintain accurate and well-organized records and electronic laboratory notebook.
  • Actively contribute to process improvements and the implementation of new technologies.
  • Perform flow cytometry assays

Required Qualifications

  • MS degree in Biology or Bioengineering (or related field) with 0-3 years of experience, or bachelor’s degree with 2-4+ years of experience in the biotechnology industry required.
  • General lab skills, including aseptic techniques and human tissue handling required
  • Lab experience and expertise in mammalian cell husbandry required, including maintaining cell cultures with good aseptic technique, media preparation, and generating/managing cell banks
  • A high level of flexibility to support various other activities and the ability to learn new techniques outside of existing field of expertise
  • Must be highly organized, have excellent attention to detail, and be able to work independently with training
  • Must be able to clearly communicate in writing and have excellent record-keeping skills

Preferred Qualifications:

  • Experience in primary cell and iPSC-derived cell culture desired
  • Strong team orientation and passion for continuous self-development
  • Experience in industry or in a startup industrial setting is preferred, including knowledge of good documentation practices
  • Previous experience with flow cytometry is not required but would be a plus
  • Must have a desire to be part of a growing organization that uses cutting-edge science


Apply For This Job

How to Apply

Please click the link at the bottom of the posting to submit an application.

Benefits

Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.