Join Our Crew

Responsibilities Include

• Conduct hands-on laboratory experiments following established protocols to maintain, expand, bank, and manage various cell lines, and generate CAR T cells.
• Perform and validate cytotoxicity and flow cytometry assays.
• Perform and validate ELISpot, ELISA, Luminex, MSD, and other assays as needed.
• Perform laboratory-associated tasks in accordance with Cabaletta Bio laboratory safety policies and SOPs.
• Oversee in vivo mouse studies and perform related ex vivo assays as needed.
• Ensure proper maintenance and cleanliness of laboratory equipment and workspaces.
• Maintain accurate, organized records and an electronic laboratory notebook.
• Analyze experimental data using basic statistical methods and software tools.
• Work collaboratively within a multidisciplinary team, actively participating in team meetings and discussions.
• Communicate experimental results and findings effectively to colleagues and supervisors through written reports and oral presentations.

Required Qualifications

• Ph.D. in Immunology, Cell Biology, Molecular Biology, or a related field with 0–2 years of experience, or a Master's degree with a minimum of 5 years of experience, or a Bachelor’s degree with a minimum of 10 years of relevant experience.
• Hands-on experience with cell culture and basic molecular biology techniques.
• General laboratory skills, including aseptic techniques and human tissue handling.
• Prior experience and proficiency with mammalian cell culture using aseptic techniques.
• Experience with primary cell husbandry, cytotoxicity assays, and flow cytometry.
• Prior involvement in animal studies or hands-on animal handling is advantageous.
• Highly organized with the ability to work independently.
• High level of flexibility to support a variety of activities and the ability to learn new techniques outside of existing areas of expertise.
• Strong team orientation and passion for continuous self-development.
• Excellent organizational skills, attention to detail, and the ability to follow protocols accurately.
• Effective written and verbal communication skills to share experimental findings and collaborate with team members.
• Extensive hands-on experience with primary immune cell cultures and related assays is advantageous.
• Experience working in a research or industry setting related to immunology and/or cell therapy.
• Experience in the biotechnology industry or a startup environment.
• Enthusiasm for learning and contributing to innovative research in the field of CAR T cell therapy.

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