Our RESETTM clinical trials with rese-cel (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, myasthenia gravis, and pemphigus vulgaris are now recruiting.

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Senior Director, Field Medical Affairs Team Lead

About the Position

We are seeking a highly motivated and experienced Senior Director, Field Medical Affairs Team Lead to lead the strategic development, build-out, and execution of the field medical organization in support of rese-cel in myositis and other autoimmune diseases. This leader will play a critical role in shaping field medical strategy, generating scientific insights, and establishing strong relationships with trial investigators, key opinion leaders (KOLs) and cell therapy treatment centers in a highly specialized and evolving therapeutic area.

This position requires deep expertise in cell therapy, strong leadership capabilities, and experience in launching cellular therapies, including building teams, developing field strategies, and aligning cross-functional stakeholders.

Responsibilities Include

Leadership & Team Development

  • Build, lead, and mentor a high-performing MSL team aligned with pre-launch and launch objectives
  • Establish team structure, hiring plans, onboarding, and training programs tailored to cell therapy complexities
  • Foster a culture of scientific excellence, compliance, collaboration, and continuous learning
  • Set performance expectations and ensure execution against strategic medical goals

Medical Strategy & Execution

  • Develop and implement the field medical strategy for rese-cel in alignment with medical and business plans
  • Translate clinical and scientific data into impactful field engagement strategies
  • Ensure readiness for launch, including scientific messaging, training materials, and KOL engagement plans
  • Lead insight generation and ensure actionable feedback is integrated into broader medical and commercial strategies

KOL & External Engagement

  • Oversee strategic engagement with KOLs, investigators, and key cell therapy treatment centers
  • Guide MSL team in delivering high-quality scientific exchange and managing complex clinical discussions
  • Support advisory boards, investigator meetings, and scientific forums (including medical conferences) as appropriate
  • Identify emerging thought leaders and key institutions in the cell therapy ecosystem

Cross-Functional Collaboration

  • Partner closely with Clinical Development, Clinical Operations, Commercial, Market Access, and Compliance Teams in order to achieve company objectives for clinical trial execution and pre-launch planning
  • Provide field insights to inform clinical trial design, evidence generation, and access strategies
  • Support pre-launch planning, including disease state education and treatment pathway mapping
  • Ensure alignment between field medical activities and broader organizational objectives

Pre-Launch & Launch Readiness

  • Participate in the development of launch readiness plans from a field medical affairs perspective
  • Anticipate and address barriers related to cell therapy adoption (e.g., site readiness, logistics, safety concerns)
  • Have an understanding of the national and regional healthcare and access environment
  • Contribute to scientific narrative development and publication strategy
  • Ensure compliance with all regulatory and legal requirements

Operational Excellence

  • Develop and manage budgets, KPIs, and reporting frameworks for the MSL organization
  • Implement systems and tools to optimize field medical effectiveness
  • Ensure adherence to compliance standards and company policies
  • Monitor competitive landscape and evolving clinical data

Required Qualifications

  • Advanced scientific degree (PharmD, PhD, MD, DO) with at least 10 years of experience in the pharma/biotech industry
  • Minimum of 8 years’ experience as a Medical Science Liaison and 3-5 years leading a team of Medical Science Liaisons within the cell therapy space is required
  • Experience in cell therapy site certifications for commercialization is highly desirable
  • Therapeutic area expertise in immunology or autoimmune diseases is desirable but not required
  • Demonstrated ability to build and maintain relationships with internal and external stakeholders, fostering collaboration and alignment
  • Proven track record of developing and executing medical affairs strategies to support product development, launch, and lifecycle management
  • Experience with developing and implementing KPIs for field engagement
  • Expertise in the use of Customer Relationship Management tools (i.e. Veeva CRM)
  • Excellent communication skills, with the ability to distill complex scientific concepts into clear, concise messages for KOLs and diverse audiences
  • Familiarity with regulatory requirements and ethical standards governing scientific research and development
  • Strategic thinking and problem-solving abilities, with a focus on driving innovation and achieving organizational objectives
  • Must be able to influence in a matrixed environment
  • Flexibility and adaptability to work in a dynamic, fast-paced environment, managing multiple projects simultaneously
  • Remote, field-based role with expected travel ~50% (mostly within US). Must be able to work Eastern Time hours, regardless of location


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How to Apply

Please click the link at the bottom of the posting to submit an application.

Benefits

Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.