Our RESETTM clinical trials with rese-cel (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, myasthenia gravis, and pemphigus vulgaris are now recruiting.

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Senior Research Associate, Analytical Development

About the Position

This role is located in Center City, Philadelphia.

Reporting to the Associate Principal Scientist, Analytical Development, the experienced and motivated Senior Research Associate plays a key role in supporting activities of routine analytical testing and method qualification for our rese-cel clinical program.  This individual is a skilled scientist with a background in biology and experience in QC testing for lentiviral vector and CAR-T cells and method qualification.

Responsibilities Include

  • Perform quality control testing to evaluate lentiviral vectors, CAR-T cells and stability samples generated by internal groups and external partners.
  • Assist in developing analytical methods for the characterization and release of lentiviral vectors and CAR-T cells.
  • Assist to Identify and implement opportunities for analytical method improvement and participate optimization of existing analytical methods to enhance sensitivity and efficiency.
  • Perform method qualification studies in accordance with regulatory guidelines.
  • Perform general lab and equipment maintenance duties.
  • Participate in technical troubleshooting and problem investigation.
  • Prepare, evaluate, and present data internally to cross functional teams.
  • Prepare detailed and accurate documentation of experimental procedures, results, and conclusions.
  • Stay current with advances in analytical techniques and industry trends.
  • Other related duties, as assigned.

Required Qualifications

  • Bachelor’s or master’s degree in biology or closely related discipline, and with 1-3 years of experience.
  • Proficient in aseptic technique for cell culture and cell-based assays.
  • Experience in analytic techniques, including flow cytometry, qPCR/dPCR, or ELISA etc.
  • Flexible to support various analytical activities and to learn new techniques outside of existing field of expertise.
  • Experience with quality control programs for lentiviral vector and CAR-T product preferred.
  • Ability to work collaboratively in a fast-paced environment.
  • Highly organized and strong written and verbal communication skills.
  • Strong laboratory documentation practice with high scientific integrity.
  • Strong team orientation and passion for continuous self-development.
  • Experience in the biotech industry or in a startup industrial setting is preferred.


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How to Apply

Please click the link at the bottom of the posting to submit an application.

Benefits

Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.