Our RESETTM clinical trials with CABA-201 (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, and myasthenia gravis are now recruiting.

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Associate Director/Director, Protein & Molecular Biology

About the Position

Reporting to the Vice President, Preclinical Research we are seeking an experienced and motivated Associate Director/Director. The successful candidate will collaborate with cross-functional teams (Cellular Immunology, Pharmacology, CMC, etc.) to advance the current research pipeline including support and participation in ongoing preclinical IND enabling studies. Additionally, they will oversee and lead a team of individuals supporting research core operations (e.g. Plasmid/Molecular Biology core, Protein core, vector core and assay development) within the Protein and Molecular Biology group.

Responsibilities Include

  • Leadership of a team responsible for both executing R&D experiments across Cabaletta’s programs, as well as core reagent production (Plasmids, antibodies, proteins, and vectors) to enable short and long-term success.
  • Support new preclinical discovery projects by working closely with scientists across the company to identify and execute key experiments.
  • Oversee the planning, execution, documentation, and interpretation of R&D experimental laboratory work, per program timelines.
  • Lead resource planning efforts needed to meet R&D objectives, including people, equipment, supplies, and space.
  • Collaborate with cross-functional peers and senior management to set objectives, gain alignment, communicate results, and project status, and meet company objectives.
  • Actively contribute to process improvements and the implementation of new technologies by being a subject matter expert in the field of molecular biology for external collaborations.

Required Qualifications

  • PhD in Molecular Biology/ Cell Biology or another similar field
  • At least 5-10 years of scientific leadership experience, ideally in the biotech industry
  • Expertise in molecular biology, protein engineering, IgG, and immunology.
  • Previous experience in the development of cell and gene therapies highly preferred.
  • Expertise in auto immune disease highly desirable.
  • Experience in a startup industrial setting highly desirable.
  • Strong leadership skills and a track record of achievement and communication demonstrated by patents, peer reviewed publications and presentations.
  • Strong organizational skills and an ability to operate cross-functionally in agile and collaborative environments.
  • Desire to be part of a growing organization that uses cutting-edge science.
  • A high level of flexibility to support various other activities and the ability to learn and guide the team in evaluating and developing new technologies outside of existing field of expertise. 
  • Strong team orientation and passion for continuous self-development.
  • Experience in the biotech industry or in a startup industrial setting is preferred.

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How to Apply

Please click the link at the bottom of the posting to submit an application.


Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.