Our RESETTM clinical trials with CABA-201 (investigational CD19-CAR T cell therapy) in lupus, myositis, systemic sclerosis, and myasthenia gravis are now recruiting.

Join Our Crew

Senior Research Associate/ Associate Scientist, Translational Medicine

About the Position

Responsibilities Include

  • With guidance from a Senior Scientist, Translational Medicine, perform assays on clinical samples and potentially pre-clinical samples.
  • Perform qualified or validated cell-based assays (cell killing assays, etc.) on clinical samples to inform on cell product persistence and efficacy in humans.
  • Perform complex multi-color flow cytometric analysis of manufactured product and clinical samples to evaluate key biomarker expression.
  • Opportunities to perform molecular based assays on platforms including MSD, Luminex, digital PCR, etc.
  • Participate in generating, qualifying, and validating GLP-like assays and contributing to the development of corresponding SOPs.
  • Interfacing heavily with the electronic lab notebook (eLN) system and sample management system; accurately capturing data in a timely manner, ensuring data integrity and protocol compliance using an eLN.
  • Maintain GDP-compliant and detailed records for clinical sample lifecycle (receipt, usage, inventory, etc.).
  • Heavily involved in clinical sample accessioning with close attention to metadata entry.
  • Manage multiple internal projects / workstreams simultaneously.
  • Performing lab associated tasks in accordance with GLP and Cabaletta Bio lab safety policies and SOPs.
  • General maintenance of laboratory space and contribution to weekly activities.

Required Qualifications

  • MS degree in Biology, Immunology, Engineering or related field or Bachelor’s degree with 2+ years of experience in an academic laboratory or the biotechnology industry is required.
  • Experience with flow cytometry in some capacity; multi-colored flow panels are a plus.
  • Significant lab experience including aseptic technique, mammalian cell culture, human tissue handling required, and plated cell-based assays.
  • Must be used to following SOPs and follow good documentation practices.
  • Must be highly organized and efficient, able to work independently. Strong problem-solving skills are preferred.
  • Must be able to communicate clearly verbally and in writing.
  • Must have a desire to be part of a growing organization that uses cutting-edge science.
  • Strong team orientation and passion for continuous self-development.
  • Comfortable in a fast-paced small company environment and able to adjust workload based upon changing priorities.

Preferred Skills

  • Experience in protocol design, qualification, and SOP generation.
  • Experience with clinical sample handling and inventory management is strongly preferred.
  • Experience troubleshooting, qualifying, or validating cell-based assays, preferably in a 96 well format.
  • Experience using the IncuCyte live cell imaging platform.
  • Experience using multi-color panels for flow cytometry.
  • Experience in the biotechnology industry or in a startup industrial setting.
  • Previous experience with GLP/GCP & ICH regulations.
  • Prior use of an electronic laboratory notebook system; involvement in system development is a plus.

Apply For This Job

How to Apply

Please click the link at the bottom of the posting to submit an application.


Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.