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Senior Research Associate/Associate Scientist, Cellular Immunology

Philadelphia, PA

About the Position

We are seeking an experienced, motivated, and highly skilled Senior Research Associate or Associate Scientist to join our Preclinical Research team. Under scientific and technical supervision, the candidate will perform various cell-based assays and maintain cell lines to contribute to the discovery and development of novel therapeutics at Cabaletta. The position offers growth into additional areas such as process development and molecular biology, immunology, and cell therapy. The position involves both technical and operational responsibilities.

Responsibilities Include

  • Maintain and expand, bank, and manage various cell lines.
  • Perform and optimize cytotoxicity and flow cytometry assays as needed.
  • Culture T-cells and CAR-Ts to support in vitro assays.
  • Manage multiple internal projects for Analytical and Manufacturing Sciences and collaborate with external sources.
  • Actively contribute to process improvements and the implementation of new technologies.
  • Perform lab associated tasks in accordance with cGLP and Cabaletta Bio lab safety policies.
  • Maintain accurate and well-organized records and electronic laboratory notebook.

Required Qualifications

  • B.S. or M.S. in Biology (or related discipline) with a minimum of 2+ years of biotechnology experience preferred.
  • General lab skills including sterile techniques and human tissue handling required.
  • Must have prior experience and be highly skilled at mammalian cell culture (aseptic techniques).
  • Significant lab experience and expertise in cell husbandry required: maintaining cell culture, media preparation, generating and managing cell stocks and banking.
  • Experience in cytotoxicity assays (such as IncuCyte, xCELLigence, 51Cr or luciferase-based assays) and flow cytometry are advantageous.
  • Must be highly organized and able to work in a cross-functional team.
  • Must be able to clearly communicate in writing, must have a desire to be part of a growing organization that uses cutting-edge science.
  • A high level of flexibility to support various other activities the ability to learn new techniques outside of existing field of expertise.
  • Strong team orientation and passion for continuous self-development.
  • Experience in industry or in a startup industrial setting is preferred.

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How to Apply

Please click the link at the bottom of the posting to submit an application.


Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.