Annual report [Section 13 and 15(d), not S-K Item 405]

Leases

v3.26.1
Leases
12 Months Ended
Dec. 31, 2025
Leases [Abstract]  
Leases

9. Leases

The Company leases office and laboratory space and has two manufacturing agreements that have been determined to include embedded leases.

Operating lease commitments

The Company leases office and laboratory space which include rent escalations and are subject to additional variable charges, including common area maintenance, property taxes and property insurance. Given the variable nature of such costs, they are recognized as expense as incurred. Additionally, some of the Company’s leases are subject to certain fixed fees which the Company has determined to be non-lease components. The Company has elected the practical expedient to account for lease and non-lease components as a single-lease component and has included fixed payments related to non-lease components in calculating the operating lease liability. The lease term

for our laboratory space was extended in October 2025 through November 2026 resulting in an increase of the right-of-use asset and lease liability of $787.

Finance lease commitments - Embedded leases

As described further in Note 7, in August 2023, the Company entered into new work orders under the Minaris Agreement for Minaris to serve as one of the Company’s cell processing manufacturing partners for the global clinical development of rese-cel. Minaris converted the Company’s non-dedicated suite to a Dedicated Suite for GMP manufacturing for the Company’s rese-cel and MuSK-CAART programs, for an initial term of 18 months. The terms of the August 2023 work orders included both fixed costs and contingent variable costs. The lease commenced October 1, 2023. In 2024, the Company remeasured the lease following the resolution of the contingency related to variable costs and an amendment to the 2023 work order, which extended the term of the agreement by an additional 18 months through August 2026. The Company may terminate the Dedicated Suite lease for convenience with six months’ prior written notice and up to a $1,080 termination fee if both the rese-cel and MuSK-CAART work orders are terminated. In February 2026, the Company notified Minaris that it intended to permit the term to expire in August 2026.

As described further in Note 7, in December 2024, the Company entered into the Lonza Agreement with Lonza to serve as one of the Company's cell processing manufacturing partners. Under the initial work order, Lonza will perform cell therapy manufacturing activities for the CAR-T cell therapy product rese-cel for a term of 12 months with the ability to extend the manufacturing period subject to the terms of the Lonza Agreement. The Lonza Agreement was evaluated under ASC 842 and determined to contain an embedded finance lease commencing in March 2025, resulting in the recognition of a right-of-use asset and lease liability of $14,934. As of December 31, 2025, the Company extended the lease term in accordance with the Lonza Agreement resulting in an increase of the right-of-use asset and lease liability of $6,137.

Summary of leases under ASC 842

The following table contains information pertaining to the Company’s operating and finance leases for the years ended December 31, 2025 and 2024.

 

 

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

Finance leases

 

 

 

 

 

 

Interest expense

 

$

2,004

 

 

$

748

 

Amortization expense

 

 

12,391

 

 

 

3,102

 

Total fixed finance lease cost

 

$

14,395

 

 

$

3,850

 

Variable lease cost

 

 

5,508

 

 

 

930

 

Total finance lease cost

 

$

19,903

 

 

$

4,780

 

Operating leases

 

 

 

 

 

 

Fixed lease cost

 

$

4,211

 

 

$

3,247

 

Total fixed operating lease cost

 

$

4,211

 

 

$

3,247

 

Variable lease cost

 

 

171

 

 

 

296

 

Short-term lease cost

 

 

34

 

 

 

750

 

Total operating lease cost

 

$

4,416

 

 

$

4,293

 

 

 

 

 

 

 

 

Cash paid in the measurement of lease liabilities

 

 

 

 

 

 

Operating cash flows used for operating leases

 

$

4,227

 

 

$

3,291

 

Operating cash flows used for finance leases

 

 

1,713

 

 

 

748

 

Financing cash flows for finance leases

 

 

6,261

 

 

 

897

 

Other information

 

 

 

 

 

 

Weighted average remaining lease term - finance leases (in years)

 

 

1.1

 

 

 

1.7

 

Weighted average discount rate - finance leases

 

 

10.7

%

 

 

11.5

%

Weighted average remaining lease term - operating leases (in years)

 

 

0.9

 

 

 

1.7

 

Weighted average discount rate - operating leases

 

 

10.3

%

 

 

11.0

%

 

For finance leases embedded in CDMO arrangements, interest expense is recognized using the effective interest method, applying the Company's incremental borrowing rate as required by ASC 842, and amortization expense is recognized on a straight-line basis over the shorter of the life of the asset or the term of the lease.

Future lease payments under the non-cancelable leases as of December 31, 2025 are as follows:
 

 

 

Finance Leases

 

 

Operating Leases

 

2026

 

$

21,914

 

 

$

3,633

 

2027

 

 

3,280

 

 

 

 

     Total undiscounted lease payments

 

 

25,194

 

 

 

3,633

 

Less imputed interest

 

 

(1,557

)

 

 

(172

)

     Total lease liability

 

$

23,637

 

 

$

3,461