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Lab Manager

Philadelphia, PA

About the Position

Reporting to the Head of Core Lab Activities (CLA), we are seeking an experienced and motivated Lab Manager to set up and manage newly established CMC facilities for the company. The position involves both technical and operational responsibilities.

Responsibilities Include

  • Set up and maintain operations of the CMC labs, including management of day-to-day activities and coordinating meetings with internal and external partners.
  • Participate and coordinate involvement in daily lab tasks, including scheduling equipment maintenance.
  • Oversee operation and maintenance of essential equipment, and monitor CMC service records and contracts.
  • Onboard new CMC scientists including lab safety training, building tours, and equipment usage training.
  • Coordinates shipping and receiving CMC materials with external vendors.
  • Manage inventory supply for CMC lab spaces, working in conjunction with the Research Lab Manager for shared resources, and act as primary resource for purchasing laboratory resources for CMC related activities.
  • Manage CMC consumable inventory and organize stock rooms.
  • Assist in optimizing existing lab space to better improve workflows and space usage.
  • Develop, implement, and maintain laboratory guidelines and standard operating procedures consistent with GXP requirements.
  • With support from Cabaletta Compliance and Quality teams, ensure compliance with local, state, and federal safety regulations; participate in training personnel on compliance in lab safety, conduct, and standards.
  • Facilitate internal and external audits, including being liaison between lab personnel and visiting individuals.
  • Manage room maintenance and cleanliness and ensure lab spaces are organized and functional.
  • Act as point person between lab personnel and Core Lab Activities.
  • Must be able to lead CMC projects independently and work collaboratively with Research Lab Manager to ensure cohesive environment.

Required Qualifications

  • BS degree or higher with 3-5 years of laboratory management or equivalent industry experience.
  • Direct involvement in starting up lab facilities with biologics development.
  • Knowledgeable of up-to-date GXP guidelines, and lab safety/training requirements.
  • Comfortable with immunological assays and biotechnology, including experience with cell culture, cell processing, and cell based functional assays.
  • Highly organized and efficient with a curiosity to be a part of cutting-edge science.
  • Must be able to move gas canisters including LN2, CO2, and compressed air NOTE: Full LN2 tanks can weigh a significant amount – tanks are placed on wheeled platforms and will be rolled over smooth flooring.
  • Must be able to lift 50lb off the ground, and up to 15lb overhead for storage room maintenance.
  • Experienced using ELN and LIMS systems.
  • Strong team orientation and passion for continuous self-development.
  • Experience in industry or in a startup industrial setting is preferred.

Preferred Skills

  • Experience organizing new laboratory space, plotting workflows, and new equipment installation.
  • Equipment demonstration and scheduling as new projects are brought online.

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How to Apply

Please click the link at the bottom of the posting to submit an application.


Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.