Join Our Crew

Associate Scientist/Scientist, MSAT

Philadelphia, PA

About the Position

The MSAT/Process Development group is seeking a motivated Associate Scientist/Scientist, MSAT who will be responsible for directing cell therapy product candidates through cGMP process development. This position will interact with internal and external partners and require up to 10% domestic travel, as well as occasional weekend and overtime work.

Responsibilities Include

  • Independently design and execute process development experimental plans, provide associated protocols and final reports as needed, and present updates and data to teams.
  • Perform cell-based analytical assays as needed to support PD work.
  • Accurately capture and analyze data in a timely manner, ensuring data integrity and protocol compliance.
  • Maintain all individual training requirements in a compliant state.
  • Support phase-appropriate cell therapy production processes using QBD principles.
  • Identify and evaluate new technologies to improve manufacturing outcomes such as: reduced costs, increased throughput, and enhanced quality.
  • Maintain laboratory material and sample inventory, support the planning of MSAT process development materials needs and coordinate purchasing with lab manager.
  • Support the transfer of process to CMO for early phase cGMP clinical manufacturing as needed.

Required Qualifications

  • S. with 3 + years or M.S. with 1 + years’ experience within biologics process development and manufacturing under cGMP processes.
  • Previous experience and working knowledge of T-cells, immunological cell therapies, and various gene delivery techniques.
  • Demonstrated experience with cell therapy manufacturing and process development/optimization is required.
  • Good coordination and communication skills are required.
  • Experience with aseptic technique in a BSL-2 laboratory is required.
  • Good working knowledge in cGMP manufacturing of biological process and ICH regulations, as well as IND/BLA submissions is preferred.
  • Breadth of experience with multiple cell processors, bioreactors, and other common cell therapy equipment is preferred.
  • Candidate should be highly organized and efficient, able to work independently. Strong problem-solving skills are preferred.
  • Experience maintaining laboratory notebooks, notably electronic lab notebooks, is preferred.
  • Experience in flow cytometry and cell-based bioassays is a plus.
  • Experience in DOE and associated software, along with other statistical analysis techniques, is a plus.
  • Candidate should have the ability to coordinate parallel tasks across multiple projects, demonstrating prioritization.

How to Apply

Please email directly to submit an application.

Please include your CV along with the title of the position you are applying for.


Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.