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Scientist, Analytical Development

Philadelphia, PA

About the Position

Reporting to the Director, Analytical Development, this experienced and motivated Scientist will support phase-appropriate activities of analytical assays to CAAR-T manufacturing production, lentiviral vector production, new gene transfer/gene editing methodologies and clinical programs.

Responsibilities Include

  • Optimize, qualify, and validate analytical methods utilizing flow cytometry, qPCR/digital PCR, cytotoxicity, ELISA or other advanced technologies, as required to evaluate purity, identity, potency of lentiviral vectors and CAAR-T cells.
  • Execute quality control assays to analyze lentiviral vectors and CAAR-T cells manufactured by external partners.
  • Develop new analytical tests to assess advanced gene transfer and gene editing modalities.
  • Assist to author analytical development report, assay validation report and other technical documents for technical correctness and regulatory compliance.
  • Participate in technical troubleshooting and problem investigation.
  • Prepare, evaluate, and present data internally to cross functional teams.

Required Qualifications

  • Master’s degree in Biology or closely related discipline, and with 3-5 years of experience or Ph.D. with 1 + years of experience within a relevant industry
  • Relevant hands-on experience with flow cytometry, qPCR/ddPCR and ELISA.
  • Experience with analytical assay development or quality control programs for cell or gene therapy products, including lentiviral vectors or CAR-T products.
  • Must be highly organized and able to work independently.
  • Must be able to clearly communicate in writing, must have a desire to be part of a growing organization that uses cutting-edge science.
  • A high level of flexibility to support various other activities and ability to learn new techniques outside of existing field of expertise.
  • Strong team orientation, science curiosity and passion for continuous self-development.
  • Strong laboratory documentation experience.
  • Familiar with GLP/GMP requirements of biopharmaceutical manufacturing.

How to Apply

Please email careers@cabalettabio.com directly to submit an application.

Please include your CV along with the title of the position you are applying for.

Benefits

Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.

Equal Opportunity Employer

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.