Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Cabaletta Bio, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

 

     Security
Type
 

Security

Class Title

  Fee
Calculation
or Carry
Forward
Rule
  Amount
Registered (1)
  Proposed
Maximum
Offering
Price Per
Unit (2)
 

Maximum

Aggregate

Offering

Price

  Fee
Rate
 

Amount of

Registration
Fee

  Carry
Forward
Form
Type
  Carry
Forward
File
Number
  Carry
Forward
Initial
Effective
Date
 

Filing Fee

Previously

Paid In

Connection

with

Unsold

Securities

to be

Carried

Forward

 

Newly Registered Securities

                         

Fees to Be 

Paid

  Equity   Common Stock, par value $0.00001 per share (3)                              
                         

Fees to Be 

Paid

  Equity   Preferred Stock, par value  $0.00001 per share (4)                              
                         

Fees to Be 

Paid

  Debt   Debt Securities (5)                              
                         

Fees to Be 

Paid

  Other   Warrants (6)                              
                         

Fees to Be 

Paid

  Other   Units (7)                              
                         

Fees to be 

Paid

  Unallocated (Universal Shelf)    (1)   457(o)   $400,000,000     $400,000,000   0.00015310    $61,240.00                
                         
Fees Previously Paid    Equity   Common Stock, par value $0.00001 per share   457(o)       $194,766,310.00      $28,747.51 (8)                 
                   
    Total Offering Amounts        $400,000,000       $61,240.00                
                   
    Total Fees Previously Paid                $28,747.51                
                   
    Total Fee Offsets                               
                   
    Net Fee Due                $32,492.49                


(1)

The amount to be registered consists of up to $400,000,000 of an indeterminate amount of common stock, preferred stock, debt securities, warrants and/or units. There is also being registered hereunder such currently indeterminate number of (i) shares of common stock or other securities of the registrant as may be issued upon conversion of, or in exchange for, convertible or exchangeable debt securities and/or preferred stock registered hereby, or (ii) shares of debt securities, common stock, preferred stock or units as may be issued upon exercise of warrants registered hereby, as the case may be, including under any applicable antidilution provisions. Any securities registered hereunder may be sold separately or together with other securities registered hereunder. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this registration statement also covers any additional securities that may be offered or issued in connection with any stock split, stock dividend or pursuant to anti-dilution provisions of any of the securities. Separate consideration may or may not be received for securities that are issuable upon conversion, exercise or exchange of other securities.

(2)

The proposed maximum offering price per security will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security pursuant to General Instruction II.D. of Form S-3 under the Securities Act.

(3)

Including such indeterminate amount of common stock as may be issued from time to time at indeterminate prices or upon conversion of debt securities and/or preferred stock registered hereby, or upon exercise of warrants registered hereby, as the case may be.

(4)

Including such indeterminate amount of preferred stock as may be issued from time to time at indeterminate prices or upon conversion of debt securities and/or preferred stock registered hereby, or upon exercise of warrants registered hereby, as the case may be.

(5)

Including such indeterminate principal amount of debt securities as may be issued from time to time at indeterminate prices or upon exercise of warrants registered hereby, as the case may be.

(6)

Warrants may be sold separately or together with any of the securities registered hereby and may be exercisable for shares of common stock, preferred stock, debt securities, or units registered hereby. Because the warrants will provide a right only to purchase such securities offered hereunder, no additional registration fee is required.

(7)

Each unit will be issued under a unit agreement and will represent an interest in two or more securities registered pursuant to this registration statement, which may or may not be separable from one another. Because the units will provide a right only to purchase such securities offered hereunder, no additional registration fee is required.

(8)

The $400,000,000 of securities registered pursuant to this registration statement includes unsold securities previously registered on this registration statement on March 21, 2024 (the “Original Registration Statement”). The Original Registration Statement registered the offer and sale of up to $200,000,000 in shares of the registrant’s common stock that may be issued and sold under a sales agreement with Cowen and Company, LLC. The registrant previously paid a fee of $29,520 related to such $200,000,000 in shares of common stock. Of such shares of common stock, $194,766,310 remain unsold (the “Unsold Shelf Securities”). The registrant has determined to include in this registration statement all of the Unsold Shelf Securities.